Acetyl Hexapeptide-8


Our acetyl hexapeptide-8 has been recognized by CIR (Cosmetic Ingredient Review) in its safety assessment report of acetyl hexapeptide-8. Free samples are available to order. Limit one per customer.

  • 0.2 g of pure powder (purity >95%) Free Sample
  • 25 ml of 2,000 ppm (0.2%) solution Free Sample

We provide large-scale peptide manufacturing (ISO9001) with USA-based shipping and service. All peptides are produced by our patented advanced liquid-phase technology under a GMP standard environment.

Please order the sample from the dropdown list below. See below for more product details and documents.



Active Peptide is a leading peptide manufacturer and provide USA-based shipping, customer service, and technical support. All peptides are produced under a GMP standard environment.
INCI Name: Acetyl Hexapeptide-8
  • CAS    616204-22-9
  • Sequence   Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2
  • Cat. No. AP106003.
  • Other Names   Ac-Hexapeptide-8; Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2
Applications and Properties:

The first anti-wrinkle hexapeptide with a botox-like mechanism of action. It reduces the depth of the wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes.

It is a safer, cheaper, and milder alternative to botox, topically targeting the same wrinkle-formation mechanism in a very different way, with comparable efficacy but leaves aside the risks, the injections and the high cost.

Acetyl Hexapeptide-8 Powder Specifications:

Acetyl Hexapeptide-8 Solution Specifications:

Mechanisms of Action

One of the most striking signs of skin aging is increased wrinkling of the face. This can occur naturally over time and is identified by certain biochemical, histological and physiological changes that are amplified by environmental exposure and other secondary factors as the pull of gravity or repeated facial movements caused by the contraction of the muscles of facial expression.

Muscles are contracted when they receive neurotransmitter release from inside a vesicle.  Acetyl Hexapeptide-8 mimics the N-terminal end of SNAP-25 and it competes with the natural protein for a position in the SNARE  complex.  If the SNARE complex is slightly destabilized, the vesicle can not release neurotransmitters efficiently  and therefore  muscle  contraction  is  attenuated, preventing the formation of lines and wrinkles.

Contact us for a COA, MSDS, Tech Data Sheet, and Tips for Formulation.

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Our Brand is Cited by CIR (Cosmetic Ingredient Review) 

Acetyl Hexapeptide-8

Additional information

Sample Size

0.2g of Pure Powder Free Sample, 25 mL of 0.2% (2,000 ppm) Solution Free Sample

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