Description
INCI Name: Nonapeptide-1
- CAS 158563-45-2
- Sequence Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2
- Cat No. AP109001
Nonapeptide-1 Powder Specifications:
Nonapeptide-1 Solution Specifications:
Cosmetic Applications and Properties:
- Prevents further activation of tyrosinase & thus blocks melanin synthesis for better control over skin tone & brown spots
- Prevents hyperproduction of melanin
- Whitening activity proven on Asian skin
Mechanisms of Action
- Antagonist of α-MSH
- Prevents tyrosinase activity
Nonapeptide-1 is a brand new skin lightening biomimetic peptide which works through the antagonism to alpha melanocyte stimulating hormone, meaning, it does not allow the hormone signal to tell the melanocyte to produce melanin, thus preventing and lightening hyperpigmentation.
Nonapeptide-1 inhibits by 33% the synthesis of melanin induced by α-MSH. Tyrosinase inhibition reduces the formation of unwanted pigmentation allowing for control over skin tone and brown spots.
Nonapeptide-1 is a biomimetic peptide antagonist specific of the α-MSH. Biomimetic peptides are identical to the skin’s peptides, and are acting on the physiological mechanisms of the skin with a high specificity. Nonapeptide-1 competes against the natural ligand (a-MSH) on it’s specific receptor(MC1-R) by preventing any further activation of the tyrosinase, and thus blocking melanin synthesis.
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