INCI Name: Alanine/Histidine/Lysine Polypeptide Copper
- Sequence： Ala-His-Lys.Cu.xHAc
- Cat No. AP103003
- Other Names: Copper Tripeptide-3; Ala-His-Lys
AHK-Cu is an analogue of GHK-Cu and has a stronger effect on hair growth. While AHK-Cu is used in skin-care, it is generally used more for both scalp and hair care than GHK-Cu.
Mechanisms of Action:
There are many primary mechanisms, such as boosting the number (proliferation) of fibroblasts and increasing the production of vascular endothelial growth factor (VEGF), a substance that allows the formation of new blood vessels. Copper peptides also reduce the secretion of transforming growth factor-beta1 within the fibroblasts. Reducing this secretion is crucial to void the negative effects of DHT.
The ultimate result is less oxidative stress (free-radical attack) and stimulation of hair growth by the dermal papilla cells. It is oxidative stress that stimulates elevated DHT formation in scalp follicles. This copper complex inhibits oxidative stress by raising the production of SOD (Superoxide dismutase), which in turn neutralizes the potent free-radical superoxide.
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