INCI Name: Palmitoyl Tetrapeptide-7
- CAS 221227-05-0
- Sequence Pal-Gly-Gln-Pro-Arg-OH
- Cat No. AP104001
- Other Names: Pal-GQPR
Pal-GQPR Solution Specifications:
Applications and Properties:
Palmitoyl tetrapeptide-7 is a type of synthetic peptide compound which combines several chains of amino acids to reduce skin inflammation and accompanying skin damage. This peptide compound is also believed to stimulate the regeneration of collagen fibers in the dermis by acting as a sort of cellular messenger. It is mainly used in anti-aging products for its ability to lighten skin, improve skin elasticity, and reduce the appearance of uneven skin tones.
It can be used separately or in combination with palmitoyl tripeptide-1 as a cosmetic anti-aging active ingredient.
- The higher concentration of this chemical in beauty products may reduce the production of interleukin to up to 40 percent. Interleukin is a chemical often associated with inflammation, as the body creates it in response to damage. For example, skin cells damaged due to the over exposure to the UV rays can cause the production of this chemical, leading to cell deterioration from inflammation. By blocking this chemical, palmitoyl tetrapeptide 7 relieves some of the chemical pressure on the skin and allows it to heal faster.
- Palmitoyl tetrapeptide-7 may also reduce problems with skin roughness, fine lines, thin skin and wrinkles.
- The proper proportion of palmitoyl tetrapeptide-7 and palmitoyl-oligopeptide in cosmetic products induces natural collagen production for skin healing and rejuvenation.
- May help treat rosacea.
- Reduce the appearance of uneven skin tones
Mechanisms of Action
Palmitoyl Tetrapeptide-7 is a synthetic peptide comprised of four amino acids that is used in beauty products and cosmetics to suppress the production of excess interleukins, the chemical messengers which trigger the body’s acute inflammatory response. This can lead to glycation damage, or the process by which glucose links with proteins and causes them to bind together, stiffening tissues. This negatively affects the skin’s support system, comprised of collagen, elastin and other proteins, and leads to wrinkles, sagging, and uneven skin tone.
Studies have shown that Palmitoyl Tetrapeptide-7 can slow or suppress the production of excess interleukins, therefore inhibiting unnecessary inappropriate inflammatory responses and glycation damage. In vitro, scientists found that “Palmitoyl Tetrapeptide-7 induced a marked dose-dependent reduction in interleukin production. The higher the concentration of Palmitoyl Tetrapeptide 7, the greater the reduction in interleukin production up to 40%.” UV radiation is also known to accelerate interleukin production. Cells exposed to UV radiation and then treated with Palmitoyl Tetrapeptide-7 saw an 86% reduction of interleukin production.
Palmitoyl Tetrapeptide-7 is used in conjunction with Palmitoyl-Oligopeptide. Together, they can boost the growth of the connective tissues and naturally increasing the production of collagen in the skin; when the production of collagen is increased, the skin can heal and rejuvenate itself.
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